Handbook on Business Information Systems

By Angappa Gunasekaran
Publisher: World Scientific Publishing Company

Number Of Pages: 960
Publication Date: 2010-04-27
ISBN-10 : 9812836055

Description
This handbook covers the vast field of business information systems, focusing particularly on developing information systems to capture and integrate information technology together with the people and their businesses.

Part I of the book, Health Care Information Systems , focuses on providing global leadership for the optimal use of health care information technology (IT). It provides knowledge about the best use of information systems for the betterment of health care services.

Part II, Business Process Information Systems , extends the previous theory in the area of process development by recognizing that improvements in intra-organizational business processes need to be complemented by corresponding improvements in inter-organizational processes.

Part III deals with Industrial Data and Management Systems and captures the main challenges faced by the industry, such as the changes in the operations paradigm of manufacturing and service organizations. Finally, Part IV, Evaluation of Business Information Systems , discusses the empirical investigation into the adoption of systems development methodologies and the security pattern of the business systems along with the mathematical models.

Handbook on Business Information Systems

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PDF For Pharmaceutical Microscopy

By Robert Allen Carlton
Sрringеr | 2011 | ISBN: 1441988300 9781441988300

337 pages | PDF| 9 MB

Microscopy plays an integral role in the research and development of new medicines. Pharmaceutical Microscopy describes a wide variety of techniques together with numerous practical applications of importance in drug development.

The first section presents general methods and applications with an emphasis on the physical science aspects. Techniques covered include optical crystallography, thermal microscopy, scanning electron microscopy, energy dispersive x-ray spectrometry, microspectroscopy (infrared and Raman), and particle size and shape by image analysis.

The second section presents applications of these techniques to specific topics of pharmaceutical interest, including studies of polymorphism, particle size and shape analysis, and contaminant identification. Pharmaceutical Microscopy is designed for those scientists who must use these techniques to solve pharmaceutical problems but do not need to become expert microscopists. Consequently, each section has exercises designed to teach the reader how to use and apply the techniques in the book.

Although the focus is on pharmaceutical development, workers in other fields such as food science and organic chemistry will also benefit from the discussion of techniques and the exercises.Provides comprehensive coverage of key microscopy techniques used in pharmaceutical development Helps the reader to solve specific problems in pharmaceutical quality assuranceOriented and designed for pharmaceutical scientists who need to use microscopy but are not expert microscopistsIncludes a large number of practical exercises to give the reader hands-on experience with the techniquesWritten by an author with 21 years of experience in the pharmaceutical industry

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Pharmaceutical Microscopy

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Modern Pharmaceutical Industry: A Primer

By Thomas M. Jacobsen, Albert I. Wertheimer
Publisher: Jones & Bartlett Publishers

Pages: 320, Date: 2009-06-05
ISBN-10 / ASIN: 0763766364

Description:
Modern Pharmaceutical Industry: A Primer comprehensively explains the broad range of divisions in the complex pharmaceutical industry. Experts actively involved in each component discuss their own contribution to a pharmaceutical company's work and success.

Divisions include regulatory affairs, research and development, intellectual property, pricing, marketing, generics, OTC, and more. The seventeen chapters included in this resource offer a wide range of topics, from discovery and formulation to post-approval and legal.

Readers will be given a detailed look at the structure of a contemporary drug company and a thorough understanding of what goes on behind the scenes. Modern Pharmaceutical Industry: A Primer is a valuable resource for all pharmacy students, new hires at pharmaceutical companies, drug company management, and academic health center libraries. No other text provides a comprehensive look at one of the most dynamic industries related to the modern healthcare system.

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Modern Pharmaceutical Industry: A Primer

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Tumor Models in Cancer Research, Second Edition

By Beverly A. Teicher, Publisher: Humana Press
Pages: 600, Date: 2010-10

ISBN-10 / ASIN: 1607619679

Description:
Lilly Research Laboratories, Indianapolis, IN. Reviews the state-of-the-art of the in vivo tumor models available for cancer research and discusses the use and interpretation of tumor models and endpoints. Covers metastatic models and includes a bibliography for each in vivo tumor model. For researchers. DNLM: Neoplasms, Experimental.

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Tumor Models in Cancer Research (Cancer Drug Discovery and Development)

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Drug Use and Abuse | PDF File

By Stephen A. Maisto, Mark Galizio, Gerard J. Connors
Publisher: Wadsworth Publishing

Pages: 504, Date: 2007-02-27
ISBN-10 : 049509207X, 596 MB | PDF

Description:
DRUG USE AND ABUSE takes an interdisciplinary approach in its coverage of current drug issues. It weaves psychological, historical, cultural, social, biological, and medical perspectives -- emphasizing the idea that a drug's effects depend not only on its properties, but also on the biological and psychological characteristics of its user.

This theme is highlighted throughout, and is prominent in discussions of the individual classes of drugs, as well as in the chapters on pharmacology and psychopharmacology.

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Drug Use and Abuse

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Part 1 | Part 2 | Part 3 | Part 4 | Part 5
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Quantitative Drug Design: A Critical Introduction, Second Edition

By Yvonne C. Martin
Publisher: CRC Press, Pages: 292, Date: 2010-05-06

ISBN-10 / ASIN: 1420070991, PDF, 8 MB

Description:
Since the publication of the first edition, the field has changed dramatically. Scientists can now explicitly consider 3D features in quantitative structure-activity relationship (QSAR) studies and often have the 3D structure of the macromolecular target to guide the 3D QSAR. Improvements in computer hardware and software have also made the methods more accessible to scientists. Taking these developments into account, Quantitative Drug Design: A Critical Introduction, Second Edition shows scientists how to apply QSAR techniques at a state-of-the-art level.

New to the Second Edition

A new chapter on methods that identify the 3D conformations to use for 3D QSAR New discussions on partial least squares, multidimensional scaling, clustering, support vector machines, kNN potency prediction, and recursive partitioning Expanded case studies that include the results of data that has been re-analyzed using newer methods A new case study on the discovery of novel dopaminergics with pharmacophore mapping and CoMFA A new case study on the application of CoMFA to series in which the 3D structure of the ligand-protein complex is known

Based on the author’s four decades of experience in all areas of ligand-based computer-assisted drug design, this invaluable book describes how to transform ligand structure-activity relationships into models that predict the potency or activity/inactivity of new molecules. It will help you avoid traps when dealing with quantitative drug design.


Features

* Presents computational techniques that analyze the relationships between molecular structure and biological activity, emphasizing methods that provide a quantitative forecast of biological potency
* Discusses the physical chemistry of ligand-macromolecule interactions and the computer programs that translate a molecule’s potential to participate in these interactions into interpretable quantitative descriptors
* Covers the fundamentals of multivariate statistics and validation procedures needed to support a valid structure-activity model
* Provides detailed examples of the author’s past predictions that offer insight into the strengths and pitfalls of various approaches

Summary
Since the publication of the first edition, the field has changed dramatically. Scientists can now explicitly consider 3D features in quantitative structure-activity relationship (QSAR) studies and often have the 3D structure of the macromolecular target to guide the 3D QSAR. Improvements in computer hardware and software have also made the methods more accessible to scientists. Taking these developments into account, Quantitative Drug Design: A Critical Introduction, Second Edition shows scientists how to apply QSAR techniques at a state-of-the-art level.

New to the Second Edition

A new chapter on methods that identify the 3D conformations to use for 3D QSAR New discussions on partial least squares, multidimensional scaling, clustering, support vector machines, kNN potency prediction, and recursive partitioning Expanded case studies that include the results of data that has been re-analyzed using newer methods A new case study on the discovery of novel dopaminergics with pharmacophore mapping and CoMFA A new case study on the application of CoMFA to series in which the 3D structure of the ligand-protein complex is known

Based on the author’s four decades of experience in all areas of ligand-based computer-assisted drug design, this invaluable book describes how to transform ligand structure-activity relationships into models that predict the potency or activity/inactivity of new molecules. It will help you avoid traps when dealing with quantitative drug design.

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